Journal: American Journal of Physiology - Heart and Circulatory Physiology
Article Title: One day of environment-induced heat stress damages the murine myocardium
doi: 10.1152/ajpheart.00180.2024
Figure Lengend Snippet: Effect of environment-induced heat stress (EIHS) on mammalian target of rapamycin (mTOR) signaling. EIHS increased phosphoinositide-dependent protein kinase 1 (PDK1), phospho (p)-PDK1, p-AKT, and p-mTOR compared with thermoneutral (TN). Total AKT, total mTOR, and total p70 S6 kinase (p70S6K), phosphorylated p70S6K, total initiation factor 4E binding protein (4EBP1) and p-4EBP1 were similar between groups. Results are expressed as means ± SD. * P < 0.05; n = 8 or 9/group for PDK1 and p-PDK1. All other measures used smaller gels such that n = 6/group. One outlier was removed from TN PKD1.
Article Snippet: mTOR (7C10) , CST, No. 2983 , 1:500 , 1:1,000.
Techniques: Binding Assay